Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits
نویسندگان
چکیده
منابع مشابه
Tuning and controlling gene expression noise in synthetic gene networks
Synthetic gene networks can be used to control gene expression and cellular phenotypes in a variety of applications. In many instances, however, such networks can behave unreliably due to gene expression noise. Accordingly, there is a need to develop systematic means to tune gene expression noise, so that it can be suppressed in some cases and harnessed in others, e.g. in cellular differentiati...
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Barbara Jusiak1,2, Ramiz Daniel1,3, Fahim Farzadfard2–5, Lior Nissim1,3, Oliver Purcell2,3, Jacob Rubens1,3,5, and Timothy K. Lu1–6 1Massachusetts Institute of Technology, Research Laboratory of Electronics, Cambridge, MA 02139, USA 2Massachusetts Institute of Technology, Department of Biological Engineering, Cambridge, MA 02139, USA 3Massachusetts Institute of Technology, Synthetic Biology Cen...
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ژورنال
عنوان ژورنال: ACS Synthetic Biology
سال: 2020
ISSN: 2161-5063,2161-5063
DOI: 10.1021/acssynbio.9b00534